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Medical device R&D teams have explored the use of scCO2 for the sterilization of allograft amnion tissue as an extension of the tissue banks growing use of scCO2 for sterilization of allograft soft tissue and bone. Recent studies have focused on demonstrating an effective sterilization process for tissue while preserving cytokines. NovaSterilis, in collaboration with iFyber, initiated a study to determine the effects of the scCO2 process on the preservation of native cytokines.